Selank — Tuftsin Analogue
Thr-Lys-Pro-Arg-Pro-Gly-Pro · 10mg Research Vial
Compound Overview
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) based on the endogenous tetrapeptide tuftsin (Thr-Lys-Pro-Arg), which is derived from the Fc region of immunoglobulin G (IgG). Developed at the Institute of Molecular Genetics, Russian Academy of Sciences, Selank incorporates a C-terminal Pro-Gly-Pro extension for enhanced metabolic stability.
Mechanism of Action
GABAergic Modulation: Preclinical studies have investigated Selank for effects on GABAergic neurotransmission, including GABA transaminase activity and allosteric modulation of benzodiazepine binding sites in rodent brain tissue.
Enkephalinase Inhibition: Research has reported Selank modulation of enkephalin-degrading enzyme activity, potentially influencing endogenous opioid peptide metabolism and turnover in preclinical models.
Immunomodulatory Research: As a tuftsin analogue, Selank has been studied for effects on innate immune function, including monocyte/macrophage activation and cytokine expression profiles in cell culture models.
Published Research
- Zozulya AA et al. (2001) — Bull Exp Biol Med, 131(4):376-378. Selank effects on enkephalin-degrading enzymes.
- Semenova TP et al. (2010) — Bull Exp Biol Med, 148(3):424-426. Selank effects on serotonin metabolism in rat brain.
Citations for reference only. No therapeutic claims.
| Class | Tuftsin analogue heptapeptide |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Purity | >99% HPLC |
| Storage | -20°C dry, 2-8°C reconstituted |
Regulatory Notice
Strictly for in-vitro laboratory investigation only. Not for human or veterinary use. BioCompounds UK makes no therapeutic claims.








I’ve used it on the other half with fantastic results previously