PT-141 10mg — BioCompounds UK product tile

The three Bio Compounds UK supply formats side by side: ready-to-use disposable pen, vial, and cartridge for a re-usable pen

PT-141 10mg (Bremelanotide) — Melanocortin Receptor Agonist — Research Grade

Name: PT-141 10mg (Bremelanotide) — Melanocortin Receptor Agonist — Research Grade
Brand: BioCompounds UK
SKU: BCUK-342
Price: 19.99 GBP
Availability: InStock

Price range: £19.99 through £39.99 inc. VAT

Free shipping on orders over £100

Research-grade PT-141 (Bremelanotide) 10mg — a cyclic heptapeptide melanocortin receptor agonist with selectivity for MC3R and MC4R. Derived from the MT-2 backbone. >99% HPLC purity. UK next-day dispatch. Strictly for in-vitro laboratory research. Not for human consumption.

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SKU: N/A Categories: Full Range, Mind Health Tags: 99%+ HPLC purity, in vitro research, lyophilised peptide, melanocortin receptor agonist, research peptide, UK research use only Brand: Bio Compounds UK - BCUK

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Hormonal & Reproductive Range

PT-141 — Bremelanotide

Melanocortin Receptor Agonist · 10mg Research Vial

Compound Overview

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide melanocortin receptor agonist derived from the Melanotan II (MT-2) backbone. Unlike MT-2, PT-141 is an active metabolite that exhibits preferential binding affinity for MC3R and MC4R over MC1R and MC5R, providing a more selective pharmacological profile for melanocortin receptor subtype research.

PT-141 was originally developed at the University of Arizona and has been the subject of clinical investigation by Palatin Technologies.

Receptor Pharmacology

MC3R Activation: Expressed in hypothalamus and peripheral tissues. Investigated in energy homeostasis and autonomic nervous system research.

MC4R Activation: Expressed in CNS regions including hypothalamus, brainstem, and spinal cord. MC4R is a major research target in central melanocortin signalling studies and neuroendocrine pathway characterisation.

Reduced MC1R Activity: PT-141 shows lower affinity for MC1R compared to MT-2, making it a useful comparator tool for studying receptor subtype-specific effects.

Published Research

Hadley ME, Dorr RT (2006) — Peptides, 27(4):921-930. Review of melanocortin agonist development from MT-2 to PT-141.
Pfaus JG et al. (2004) — Proc Natl Acad Sci, 101(27):10201-10204. Preclinical characterisation of PT-141 melanocortin receptor pharmacology.

Citations for reference only. No therapeutic claims.

Class	Selective melanocortin receptor agonist
Targets	MC3R, MC4R (preferential)
Purity	>99% HPLC
Storage	-20°C dry, 2-8°C reconstituted

Regulatory Notice

Strictly for in-vitro laboratory investigation only. Not for human or veterinary use. BioCompounds UK makes no therapeutic claims.

Frequently Asked Questions

What is PT-141 (Bremelanotide)?

PT-141, also known as Bremelanotide, is a synthetic melanocortin receptor agonist. It is a cyclic heptapeptide analogue of alpha-MSH and primarily targets the MC4 receptor. It has been investigated in research relating to central nervous system signalling pathways.

What is the purity of this peptide?

BioCompounds UK supplies HPLC-verified research-grade material. Selected batches undergo independent third-party analysis by Janoshik Analytical, with current published Certificates of Analysis available on our batch verification page when applicable.

What is the half-life of PT-141?

PT-141 has an approximate half-life of 2 hours in published research models, with effects often studied within a 6-12 hour window post-administration.

How does PT-141 differ from MT-2?

Both target melanocortin receptors, but with different selectivity profiles. MT-2 (Melanotan II) is a broader MC1-5 receptor agonist studied primarily in pigmentation research. PT-141 is more selective for the MC3/MC4 receptors and is studied in distinct CNS-related pathways.

How should this peptide be stored?

Storage depends on the format you have chosen:

10mg Vial (lyophilised powder): Store at -20°C in a sealed container, away from light and moisture. Once reconstituted, keep refrigerated between 2°C and 8°C and use within approximately four weeks.
3ml Cartridge (for reusable pen): Store refrigerated between 2°C and 8°C from arrival. Once opened, use within 3 months. Keep away from light.
Disposable Ready-to-Use Pen: Store refrigerated between 2°C and 8°C from arrival. Once opened, use within 3 months. Keep away from light.

Full details are in our Peptide Storage Guide.

What formats is this available in?

This product is available in three research formats: a 10mg lyophilised vial, a 3ml cartridge for reusable research pens, and a ready-to-use disposable pen. Vials offer the most flexibility in reconstitution; cartridges and pens are calibrated for our standard equipment.

How fast is UK delivery?

Orders are typically dispatched within 24 hours via Royal Mail Tracked 24. During busier periods dispatch may extend to 48 hours. Free shipping on UK orders over £100. Full details on our Postage Guidance page.

Is this product legal in the UK?

All BioCompounds UK products are sold strictly for in-vitro laboratory research by qualified researchers aged 18 or over. They are not approved or intended for human or veterinary consumption, diagnostic, or therapeutic use. See our Terms of Purchase for full guidance.

Weight	0.050 kg

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PT-141 10mg (Bremelanotide) — Melanocortin Receptor Agonist — Research Grade