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MT-2 10mg — Melanocortin Receptor Agonist (Cyclic Heptapeptide) — Research Grade

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Research-grade MT-2 10mg — a non-selective melanocortin receptor agonist (MC1R/MC3R/MC4R/MC5R). Synthetic cyclic heptapeptide. HPLC-verified at >99% purity. UK next-day dispatch. Available as Vial, Cartridge, Disposable Pen, or Nasal format. Strictly for in-vitro laboratory research. Not for human consumption.

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MT-2 — Melanocortin Receptor Agonist

Cyclic Heptapeptide Research Compound  ·  10mg Research Vial

Available Formats

Vial
Lyophilised powder vial offering full flexibility in reconstitution volume and concentration.

Cartridge (Reusable Pen)
Pre-filled replacement cartridge compatible with standard reusable research pens. Pen sold separately.

Disposable Pen
Fully pre-loaded, self-contained research pen. Ready to use directly from packaging.

Nasal
Pre-prepared nasal delivery format for intranasal administration research protocols.


Compound Overview

MT-2 (Melanotan II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). It was originally developed at the University of Arizona by Hruby and Hadley in the 1990s as a research tool for studying melanocortin receptor pharmacology.

MT-2 is a non-selective melanocortin receptor agonist with affinity for multiple MCR subtypes (MC1R, MC3R, MC4R, MC5R). Its broad receptor binding profile has made it a widely used pharmacological tool in melanocortin system research.

Receptor Pharmacology

MC1R: Expressed on melanocytes and immune cells. MC1R activation is the primary pathway studied in melanogenesis and pigmentation research.

MC3R: Expressed in the hypothalamus and peripheral tissues. Investigated in energy homeostasis and autonomic function research.

MC4R: Expressed in central nervous system regions including the hypothalamus and brainstem. MC4R is a major research target in neuroendocrine signalling studies.

MC5R: Expressed in sebaceous glands and other exocrine tissues. Studied for its role in exocrine gland function research.

Published Research

  • Hruby VJ et al. (1995) — Journal of Medicinal Chemistry, 38(18): 3454-3461. Design and synthesis of MT-2 as a melanocortin receptor research tool.
  • Dorr RT et al. (1996) — Life Sciences, 58(20): 1777-1784. Pharmacological evaluation of MT-2 in preclinical models.

Note: Citations are provided for reference purposes only. BioCompounds UK does not make therapeutic claims.

Structural & Chemical Data

Compound ClassNon-selective melanocortin receptor agonist
StructureCyclic heptapeptide (lactam bridge)
Receptor TargetsMC1R, MC3R, MC4R, MC5R
Purity>99% verified by HPLC
Quantity10mg per unit
SolubilitySterile water / PBS
Storage (Dry)-20 C
Storage (Reconstituted)2-8 C, use within 4 weeks

Regulatory & Usage Notice

This product is supplied strictly as a research-grade reference compound for in-vitro laboratory investigation only. It is not approved, intended, or marketed for human or veterinary administration, diagnostic purposes, or therapeutic application. MT-2 is not an approved medicine in the UK or EU. Purchasers must be qualified researchers aged 18+ and agree to handle all compounds in accordance with applicable regulations and good laboratory practice (GLP). BioCompounds UK makes no therapeutic claims regarding this or any compound in its catalogue.

Frequently Asked Questions

What is MT-2 (Melanotan II)?

MT-2 (Melanotan II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). It is a broad-spectrum melanocortin receptor agonist targeting MC1, MC3, MC4, and MC5 receptors. It is widely studied in pigmentation research and melanocortin system pharmacology.

What is the purity of this peptide?

BioCompounds UK supplies HPLC-verified research-grade material. Selected batches undergo independent third-party analysis by Janoshik Analytical, with current published Certificates of Analysis available on our batch verification page when applicable.

What is the half-life of MT-2?

MT-2 has an approximate half-life of 30 minutes in published research models, though its melanocortin-receptor effects on melanogenesis have been observed to persist far longer due to downstream signalling cascades.

How does MT-2 compare to PT-141?

Both target melanocortin receptors. MT-2 is a broader MC1-MC5 agonist studied principally in pigmentation research. PT-141 (Bremelanotide) is more selective for MC3/MC4 and is studied in distinct CNS-related pathways. See our MT-2 research guide.

How should this peptide be stored?

Storage depends on the format you have chosen:

  • 10mg Vial (lyophilised powder): Store at -20°C in a sealed container, away from light and moisture. Once reconstituted, keep refrigerated between 2°C and 8°C and use within approximately four weeks.
  • 3ml Cartridge (for reusable pen): Store refrigerated between 2°C and 8°C from arrival. Once opened, use within 3 months. Keep away from light.
  • Disposable Ready-to-Use Pen: Store refrigerated between 2°C and 8°C from arrival. Once opened, use within 3 months. Keep away from light.
  • Nasal Apparatus (10mg/10ml): Store refrigerated between 2°C and 8°C from arrival. Once opened, use within 3 months. Keep upright and away from light.

Full details are in our Peptide Storage Guide.

What formats is this available in?

This product is available in four research formats: a 10mg lyophilised vial, a 3ml cartridge for reusable research pens, a ready-to-use disposable pen, and a 10mg/10ml intranasal research apparatus. The nasal format is supplied as a reconstituted solution for specific intranasal research protocols.

How fast is UK delivery?

Orders are typically dispatched within 24 hours via Royal Mail Tracked 24. During busier periods dispatch may extend to 48 hours. Free shipping on UK orders over £100. Full details on our Postage Guidance page.

Is this product legal in the UK?

All BioCompounds UK products are sold strictly for in-vitro laboratory research by qualified researchers aged 18 or over. They are not approved or intended for human or veterinary consumption, diagnostic, or therapeutic use. See our Terms of Purchase for full guidance.

Weight0.050 kg

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