Glutathione 1500mg

Available Formats

Vial
A 1500mg lyophilised powder vial for researchers who require full flexibility in reconstitution volume and concentration. Requires a compatible syringe or laboratory delivery system.

Cartridge (Reusable Pen)
A pre-filled replacement cartridge compatible with standard reusable research pens. Suitable for extended or repeat-interval protocols. Reusable pen sold separately.

Disposable Pen
A fully pre-loaded, self-contained research pen requiring no additional equipment. Ready to use directly from packaging. Suitable for short-duration protocols or laboratories trialling the pen delivery format. Dispose of responsibly after use.

Compound Overview

Glutathione (GSH) is a ubiquitous endogenous tripeptide comprised of three amino acids: L-glutamate, L-cysteine, and glycine. It serves as the primary non-protein thiol in mammalian cells and plays a critical role in maintaining cellular redox homeostasis. Synthesised naturally within the liver, glutathione has been the subject of extensive scientific investigation regarding its role in cellular protection, detoxification pathways, and mitochondrial function.

The 1500mg format is a high-yield research unit optimized for robust dose-response characterisation, cellular oxidative stress models, and comparative assays against alternative antioxidant or precursor compounds.

Mechanism of Action

Glutathione exerts its physiological and biochemical mechanisms through concurrent cellular pathways:

Direct ROS Neutralisation: Acting as a potent reducing agent, glutathione directly scavenges reactive oxygen species (ROS), hydroxyl radicals, and singlet oxygen atoms. This activity protects delicate cellular membranes, nucleic acids, and structural proteins from oxidative degradation in preclinical models.

Enzymatic Cofactor & Phase II Detoxification: Serves as an indispensable substrate for vital antioxidant enzymes, including Glutathione Peroxidase (GPx) and Glutathione S-Transferases (GST). These enzymatic pathways facilitate the neutralisation of lipid peroxides and the conjugation of electrophilic xenobiotics, rendering them water-soluble for cellular excretion.

The complete tripeptide profile distinguishes Glutathione from its precursors (e.g. N-acetyl cysteine), enabling researchers to evaluate immediate, direct-acting cellular redox adjustments without relying on rate-limiting intracellular enzymatic synthesis.

Published Research & Clinical Data

Glutathione has been evaluated across numerous scientific disciplines and in-vivo models. Key publications include:

• Richie JP Jr et al. (2015) — European Journal of Nutrition, 54(2): 251-263. A randomised, double-blind, placebo-controlled study evaluating the effects of glutathione supplementation on systemic body stores and immune biomarkers over a 6-month protocol.
• Ballatori N et al. (2009) — Biological Chemistry, 390(3): 191-214. A comprehensive biochemical review documenting glutathione transport, homeostasis, and its critical regulatory roles in cell survival and apoptotic signalling pathways.

Note: The above citations are provided for reference purposes only. BioCompounds UK does not make therapeutic claims based on clinical trial data. Researchers are encouraged to consult the primary literature directly.

Structural & Chemical Data